The palace was built in 1667 by Cesare di Antonio Moretti, a descendant of a noble family from Perugia, who died suddenly before having finished it. As proof of its incompleteness, the holes in the scaffolding remain open, closed windows and shelves without balconies.
The ancient baptismal font of Santa Margherita da Cortona is preciously preserved in the small but splendid Noble Chapel.

Since 2008, the Palazzo hosts the permanent exhibition of documents and the historical archive dedicated to the physicist Franco Rasetti, an eclectic scientist born in Pozzuolo Umbro, one of the boys of ‘Via Panisperna’, objector to the studies aimed at the realization of the atomic bomb.

In the other rooms, there is also a collection of plants from the hilly area of ​​Trasimeno, with captions on their medicinal or medical remedies, an exhibition linked to paleontology and another dedicated to the war events that involved the territory during the two world wars.

The long entrance (about 30 meters) is available for conferences, book presentations and art exhibitions by local and international artists.