The church of Saint Sebastian is actually dedicated to the two saints Sebastian and Rocco, and is located just outside the medieval walls of Paciano.
It seems that at the end of the 6th century there used to be an Oratory in this location dedicated to Saint Sebastian. Probably smaller than the recent building, the oratory was enlarged during the 15th century most likely as a way for the residents to show their gratitude to the two saints for having helped the town escape the plague. Remaining fragments of important frescoes can be linked to the school of Pietro Vannucci.